[PAST EVENT] Cheminar: Dr. Lesley Greene, ODU, "Hidden Patterns in Proteins Govern Shape and Stability"

April 22, 2022
3pm - 4pm
Integrated Science Center (ISC), Room 1127
540 Landrum Dr
Williamsburg, VA 23185Map this location
Images of speaker's face and text describing seminar title and time

Dr. Lesley Green, of ODU, is our speaker on Friday, 22 April

Hidden Patterns in Proteins Govern Shape and Stability

Understanding the molecular mechanisms by which proteins fold can be investigated by looking for hidden patterns in proteins and testing their hypothesized role in governing shape and stability. In this talk we will show how conserved networks of long-range interactions were elucidated in a group of proteins which share a common and highly populated Greek-key topology. Extensive computational studies using network science approaches and macromolecular simulations support their proposed role in governing stability and topology. This presentation also highlights the importance of changing the way we look at established views of fundamental biological molecules to address central challenges in basic science.

Lesley Greene is the Associate Dean of Graduate Studies and Associate Professor of Chemistry and Biochemistry at ODU. She earned her Ph.D. in Biochemistry and Molecular Biology at the University of Miami. She held a Post-Doctoral Research Fellowship in the Chemistry Department at the University of Oxford and Senior Research Fellow post in the Department of Structural Biology and Biochemistry at University College of London. She then joined the chemistry and biochemistry faculty at Old Dominion University.